🏛️ Verified NIH Record • Updated 2026-02-20
Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis (NCT05201638)
A Multi-Center, Randomized, Double-Blinded Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 Versus Placebo in Adults With Relapsing Multiple Sclerosis (ENSURE-2)
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Immunic AG
🩺 Plain-English Summary (8th-Grade Level)
Multi-Center, Randomized, Double-Blinded Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 versus Placebo in Adults with Relapsing Multiple Sclerosis (ENSURE-2)
Who can join: Review the eligibility criteria below.
Location: Neuro of Central Florida — Altamonte Springs, Florida
Age range: 18 Years to 55 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (76 Sites)
Showing the first 25 of 76 sites.
- Neuro of Central Florida — Altamonte Springs, Florida
- Healthcare Innovations — Coral Springs, Florida
- Heratsi Hospital Complex 1 — Yerevan,
- Saint Gregory the Illuminator Medical Center — Yerevan,
- Erebouni Medical Center — Yerevan,
- UCC of Rep of Srpska — Banja Luka,
- Cantonal Hospital Bihac Dr. Irfan Ljubijankic — Bihać,
- University Clinical Center of Sarajevo — Sarajevo,
- University Clinical Center Sarajevo — Sarajevo,
- University Clinical Center Tuzla — Tuzla,
- Astra Clinic — Tallinn,
- University Hospital Muenster, Institute Translational Neurology dept. Neurology — Münster,
- Post-Graduation Institute of Medical Education and Research (PGIMER) — Chandigarh,
- Fortis Memorial Research Institute — Gurugramam,
- Polakulath Narayanan Renai Medicity MSSH — Kochi,
- Dr Ram Manohar Lohia Institute of Medical Sciences — Lucknow,
- All India Institute of Medical Sciences — New Delhi,
- GB Pant Institute of Postgraduate Medical Education and Research — New Delhi,
- SRI Guru Ram Das Institute of Medical Sciences and Research — Punjābi Bāgh,
- DKS PGI — Raipur,
- Hospital Nacional Dos de Mayo — Lima,
- NZOZ Novo-Med — Katowice,
- NZOZ Wielospecjalistyczna Poradnia Lekarska "Synapsis" — Katowice,
- Neuro-Medic Janusz Zbrojkiewicz — Katowice,
- NZOZ Neuromed — Lublin,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis — La Jolla, California
- A Post-Authorization, Long-term Study of Ozanimod Real-world Safety — Bethesda, Maryland
- Efficacy of Diet on Quality of Life in Multiple Sclerosis — Iowa City, Iowa
Explore by condition: All Multiple Sclerosis, Relapsing-Remitting clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.