🏛️ Verified NIH Record • Updated 2025-09-29

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (NCT05211570)

A Phase 1/2 Study to Assess the Safety, Pharmacokinetics, and Efficacy of Daily Intravenous AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic Sponsor: AB Science

🩺 Plain-English Summary (8th-Grade Level)

The primary objective is to define the safety and tolerability of AB8939 in patients with AML by determining the dose-limiting toxicities, the maximum tolerated dose, and the recommended dose for dose expansion study.

Who can join: Review the eligibility criteria below.

Location: MD Anderson Cancer Center — Houston, Texas

Age range: 18 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (10 Sites)

  • MD Anderson Cancer Center — Houston, Texas
  • Institut Paoli Calmettes — Marseille,
  • National and Kapodistrian University of Athens NKUA · Department of Hematology and Bone marrow Transplantation Unit — Athens,
  • General University Hospital of Alicantet (Hospital General Universitario Dr. Balmis de Alicante) — Alicante,
  • Hospital San Pedro de Alcantara — Cáceres,
  • Hospital Universitario 12 de Octubre — Madrid,
  • Hospital Universitario Quirónsalud — Madrid,
  • MD Anderson Cancer Center Madrid — Madrid,
  • Clínica Universidad de Navarra — Pamplona,
  • Virgen del Rocío University Hospital (Hospital Universitario Virgen del Rocío) — Seville,

📞 Contact the Study Coordinator

Phone: +33(0)147200014

Email: clinical@ab-science.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Acute Myeloid Leukemia Refractory

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗