Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer (NCT05228275)
Prospective Cohort Study to Evaluate Immunologic Response Following COVID-19 Vaccination in Children, Adolescents and Young Adults With Cancer
🩺 Plain-English Summary (8th-Grade Level)
This study evaluates immunologic response following COVID-19 vaccination in children, adolescents, and young adults with cancer. Vaccines work by stimulating the body's immune cells to respond against a specific disease. The immune response produces protection from that disease. Effects from cancer and from treatments for cancer can reduce the body's natural disease fighting ability (called immunity). Factors such as vaccine type, timing of vaccine dosing related to treatment for cancer and number of vaccine doses or "boosts" (extra vaccine shots) may strengthen or diminish the body's protective immune response. This study may help researchers learn more about how the body's immune system responds to the COVID-19 vaccine when the vaccination is given during or after cancer treatment.
Who can join: Review the eligibility criteria below.
Location: Children's Hospital of Alabama — Birmingham, Alabama
Age range: 6 Months to 37 Years
🧪 Interventions in This Study
- Biospecimen Collection (PROCEDURE)
- Survey Administration (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (72 Sites)
Showing the first 25 of 72 sites.
- Children's Hospital of Alabama — Birmingham, Alabama
- Kingman Regional Medical Center — Kingman, Arizona
- UCSF Benioff Children's Hospital Oakland — Oakland, California
- Rady Children's Hospital - San Diego — San Diego, California
- Alfred I duPont Hospital for Children — Wilmington, Delaware
- Children's National Medical Center — Washington D.C., District of Columbia
- Golisano Children's Hospital of Southwest Florida — Fort Myers, Florida
- UF Health Cancer Institute - Gainesville — Gainesville, Florida
- Memorial Regional Hospital/Joe DiMaggio Children's Hospital — Hollywood, Florida
- Nemours Children's Clinic-Jacksonville — Jacksonville, Florida
- Nicklaus Children's Hospital — Miami, Florida
- Nemours Children's Hospital — Orlando, Florida
- Sacred Heart Hospital — Pensacola, Florida
- Johns Hopkins All Children's Hospital — St. Petersburg, Florida
- Tampa General Hospital — Tampa, Florida
- Saint Joseph's Hospital/Children's Hospital-Tampa — Tampa, Florida
- Kapiolani Medical Center for Women and Children — Honolulu, Hawaii
- University of Illinois — Chicago, Illinois
- OSF Children's Hospital of Illinois — Peoria, Illinois
- Maine Children's Cancer Program — Scarborough, Maine
- Sinai Hospital of Baltimore — Baltimore, Maryland
- C S Mott Children's Hospital — Ann Arbor, Michigan
- Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital — Grand Rapids, Michigan
- Bronson Methodist Hospital — Kalamazoo, Michigan
- Corewell Health Children's — Royal Oak, Michigan
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.