๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-02-06

P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors (NCT05239143)

A Phase 1 Dose Escalation and Expanded Cohort Study of P-MUC1C-ALLO1 in Adult Subjects With Advanced or Metastatic Solid Tumors

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Poseida Therapeutics, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

A Phase 1, open label, dose escalation and expanded cohort study of P-MUC1C-ALLO1 in adult subjects with advanced or metastatic epithelial derived solid tumors, including but not limited to the tumor types listed below.

Who can join: Review the eligibility criteria below.

Location: University of California, Irvine Medical Center โ€” Irvine, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (14 Sites)

  • University of California, Irvine Medical Center โ€” Irvine, California
  • Cedars Sinai Medical Center โ€” Los Angeles, California
  • University of California, San Diego โ€” San Diego, California
  • University of California, San Francisco โ€” San Francisco, California
  • Sarah Cannon Research Institute at HealthONE โ€” Denver, Colorado
  • University of Iowa Hospitals and Clinics โ€” Iowa City, Iowa
  • University of Kansas Cancer Center โ€” Westwood, Kansas
  • Cancer Center of Kansas โ€” Wichita, Kansas
  • University of Maryland Cancer Center โ€” Baltimore, Maryland
  • Dana Farber Cancer Institute โ€” Boston, Massachusetts
  • University of Nebraska Medical Center โ€” Omaha, Nebraska
  • Montefiore Medical Center โ€” The Bronx, New York
  • MD Anderson Cancer Center โ€” Houston, Texas
  • NEXT Oncology โ€” San Antonio, Texas

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—