๐๏ธ Verified NIH Record โข Updated 2026-02-06
P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors (NCT05239143)
A Phase 1 Dose Escalation and Expanded Cohort Study of P-MUC1C-ALLO1 in Adult Subjects With Advanced or Metastatic Solid Tumors
๐ต Active, Not Recruiting Phase1 ๐ Investigational Drug / Biologic Sponsor: Poseida Therapeutics, Inc.
๐ฉบ Plain-English Summary (8th-Grade Level)
A Phase 1, open label, dose escalation and expanded cohort study of P-MUC1C-ALLO1 in adult subjects with advanced or metastatic epithelial derived solid tumors, including but not limited to the tumor types listed below.
Who can join: Review the eligibility criteria below.
Location: University of California, Irvine Medical Center โ Irvine, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (14 Sites)
- University of California, Irvine Medical Center โ Irvine, California
- Cedars Sinai Medical Center โ Los Angeles, California
- University of California, San Diego โ San Diego, California
- University of California, San Francisco โ San Francisco, California
- Sarah Cannon Research Institute at HealthONE โ Denver, Colorado
- University of Iowa Hospitals and Clinics โ Iowa City, Iowa
- University of Kansas Cancer Center โ Westwood, Kansas
- Cancer Center of Kansas โ Wichita, Kansas
- University of Maryland Cancer Center โ Baltimore, Maryland
- Dana Farber Cancer Institute โ Boston, Massachusetts
- University of Nebraska Medical Center โ Omaha, Nebraska
- Montefiore Medical Center โ The Bronx, New York
- MD Anderson Cancer Center โ Houston, Texas
- NEXT Oncology โ San Antonio, Texas
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Breast Cancer
- S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer โ Anniston, Alabama
- [177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer โ Los Angeles, California
- Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery โ Durham, North Carolina
- TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B) โ Palo Alto, California
- A Multi Modality Surveillance Program for Women At High Risk for Breast Cancer โ Chicago, Illinois
- ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer โ Duarte, California
Explore by condition: All Breast Cancer clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.