Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma (NCT05253495)
Reducing the Burden of Oncologic Chemoradiotherapy And Radiation Exposure From Diagnostic Imaging by Utilizing Targeted Immunotherapy in Children, Adolescents and Young Adults With Lymphoma
🩺 Plain-English Summary (8th-Grade Level)
The addition of targeted immunotherapy will be safe and well tolerated and facilitate the reduction of anthracycline exposure while preserving lymphoma disease control in children, adolescents and young adults (CAYA) with mature B-cell non-Hodgkin lymphoma (MB-NHL) and classical Hodgkin lymphoma (cHL).
Who can join: Review the eligibility criteria below.
Location: University of Alabama — Birmingham, Alabama
Age range: 3 Years to 39 Years
🧪 Interventions in This Study
- DOC Group B (DRUG)
- Pv-COMRAD 1 and 2 Group B (DRUG)
- Pv-R-CYM 1 and 2 Group B (DRUG)
- DOC Group C (DRUG)
- MAD CPR 1 and 2 (DRUG)
- Pv-R CYVE 1 and 2 (DRUG)
- Pv-R CYVE-MTX 1 and 2 (DRUG)
- MAD CP (DRUG)
- Pv-Cytarabine/etoposide (DRUG)
- AD CP (DRUG)
- Bv-AVD-R 1 and 2: COHORT IIa (DRUG)
- Bv-NVD-R, Cycle 1-2 (DRUG)
- Bv-NVD-R, Cycle 1-4 SER (DRUG)
- Bv-AVD-R (DRUG)
- Bv-NVD-R, Cycle 1-4 RER (DRUG)
- Bv-NAVD-R, Cycle 1-2 (DRUG)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- University of Alabama — Birmingham, Alabama
- University of Flordia — Gainsville, Florida
- New York Medical College — Vallhala, New York
📞 Contact the Study Coordinator
Phone: (914) 594-2150
Email: mitchell_cairo@nymc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.