Uterine Transplant for Women With Absolute Uterine Factor Infertility (AUFI) (NCT05263076)
Uterine Transplantation and Pregnancy Induction in Women Affected by Absolute Uterine Factor Infertility
🩺 Plain-English Summary (8th-Grade Level)
Absolute Uterine Factor Infertility (AUFI) is due to congenital or surgical absence of a uterus or the presence of a nonfunctional uterus. Until 2014, the only option for women affected by Absolute Uterine Factor Infertility (AUFI) was adoption or surrogate motherhood. Uterine transplant is a new form of transplant to treat AUFI. The technique of uterus transplant was developed in Sweden with the transplantation of the uterus from a living donor to a woman affected by AUFI. Approximately 80 uterine transplantations have been performed, more than 50 of which have occurred within the past 3 years. To date, 34 children have been born from mothers who have received a living donor uterine transplant. This is a prospective study to treat Absolute Uterine Factor Infertility (AUFI) through uterine transplantation utilizing a uterus from a living or deceased donor resulting in live birth. A total of 10 biologically female (XX Karyotype) subjects will receive a uterine transplant.
Who can join: Review the eligibility criteria below.
Location: Texas Children's Hospital — Houston, Texas
Age range: 20 Years to 65 Years
🧪 Interventions in This Study
- Uterine Transplant (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Texas Children's Hospital — Houston, Texas
📞 Contact the Study Coordinator
Phone: (832) 822-1551
Email: uterustransplant@texaschildrens.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Mayer Rokitansky Kuster Hauser Syndrome
- The University of Pennsylvania Uterus Transplant for Uterine Factor Infertility Trial — Philadelphia, Pennsylvania
Explore by condition: All Mayer Rokitansky Kuster Hauser Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.