🏛️ Verified NIH Record • Updated 2026-02-04
His-Bundle Corrective Pacing in Heart Failure (NCT05265520)
🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol Sponsor: University of Rochester
🩺 Plain-English Summary (8th-Grade Level)
The investigators aim to prospectively evaluate the efficacy and mechanism of benefit of His-bundle pacing enhanced cardiac resynchronization therapy (His-CRT) vs. cardiac resynchronization therapy (BIV-CRT) in patients with heart failure and right bundle branch block (RBBB).
Who can join: Review the eligibility criteria below.
Location: University of Arizona — Phoenix, Arizona
Age range: 18 Years
🧪 Interventions in This Study
- His-CRT implantation (PROCEDURE)
- BIV-CRT implantation (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (14 Sites)
- University of Arizona — Phoenix, Arizona
- Cedars-Sinai Medical Center — Los Angeles, California
- University of South Florida — Tampa, Florida
- Northwestern Memorial Hospital — Chicago, Illinois
- Rush University Medical Center — Chicago, Illinois
- University of Chicago — Chicago, Illinois
- Valley Health System — Ridgewood, New Jersey
- Weill Cornell Medical College — New York, New York
- Mount Sinai Hospital — New York, New York
- Mission Health — Asheville, North Carolina
- University of Pennsylvania — Philadelphia, Pennsylvania
- Geisinger Wyoming Valley — Wilkes-Barre, Pennsylvania
- University of Vermont — Burlington, Vermont
- Virginia Commonwealth University — Richmond, Virginia
📞 Contact the Study Coordinator
Phone: (585) 275-1054
Email: ann.colasurdo@heart.rochester.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Right Bundle-Branch Block clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.