Mode of Exercise and Bone Biomarkers in Older Veterans (NCT05266976)
Anabolic Versus Catabolic Skeletal Effects of Endurance or Resistance Exercise in Older Veterans
🩺 Plain-English Summary (8th-Grade Level)
Adults are often encouraged to exercise to maintain or improve bone health. However, there is evidence that exercise does not always lead to increases in bone mass, and exercise could lead to bone loss under certain conditions. Endurance exercise can increase bone resorption following an exercise bout, which may explain why bone does not always favorably adapt to exercise, but it is unclear if this also happens with resistance exercise. Further, it is not known how exercise training influences blood markers of bone resorption for either endurance or resistance exercise. The purpose of this study is to determine 1) if resistance exercise causes a similar increase in bone resorption as endurance exercise; and 2) if exercise training influences the increase in bone resorption following exercise for both endurance and resistance exercise.
Who can join: Review the eligibility criteria below.
Location: Rocky Mountain Regional VA Medical Center, Aurora, CO — Aurora, Colorado
Age range: 60 Years
🧪 Interventions in This Study
- 10 Weeks of Supervised Resistance Exercise Training (BEHAVIORAL)
- 10 Weeks of Supervised Endurance Exercise Training (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Rocky Mountain Regional VA Medical Center, Aurora, CO — Aurora, Colorado
📞 Contact the Study Coordinator
Phone: (720) 848-6475
Email: sarah.wherry@va.gov
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.