Vascular Endothelial Dysfunction in Sleep Apnea (NCT05289063)
🩺 Plain-English Summary (8th-Grade Level)
This double-blind placebo-controlled parallel group randomized study design will be used to test whether 4 weeks of atorvastatin 10 mg daily reduces levels of inflammatory markers in OSA patients treated with CPAP (standard of care). The purpose of this study is to investigate: 1) whether statins reduce endothelial inflammation and pro-thrombotic conditions in OSA, including in patients adherent to CPAP (Aim 1); and 2) whether statins reduce endothelial inflammation and pro-thrombotic conditions by improving endothelial cholesterol metabolism and trafficking in OSA (Aim 2).
Who can join: Review the eligibility criteria below.
Location: Columbia University Irving Medical Center — New York, New York
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Columbia University Irving Medical Center — New York, New York
📞 Contact the Study Coordinator
Phone: (212) 543-8875
Email: sj366@cumc.columbia.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Obstructive Sleep Apnea of Adult
- Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea — Aurora, Colorado
- Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy — Birmingham, Alabama
- Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia — Calgary, Alberta
- Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA) — Mexico City,
- A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea — Rochester, Minnesota
Explore by condition: All Obstructive Sleep Apnea of Adult clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.