CASCADE-LUNG: Cancer Screening Assay Using DELFI; A Clinical Validation Study in Lung (NCT05306288)
🩺 Plain-English Summary (8th-Grade Level)
CASCADE-LUNG is a multisite, prospective, observational, blood specimen collection study in the elevated-risk lung cancer screening population. The primary objective is to demonstrate the performance characteristics, including sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the DELFI Lung Cancer Screening Test (DLCST) for the detection of pathologically-confirmed lung cancer in a screening population using LDCT, pathology, and follow-up as the reference method.
Who can join: Review the eligibility criteria below.
Location: Cullman Clinical Trials — Cullman, Alabama
Age range: 50 Years
🧪 Interventions in This Study
- Blood Sample Collection (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (67 Sites)
Showing the first 25 of 67 sites.
- Cullman Clinical Trials — Cullman, Alabama
- Science 37 (nationwide digital enrollment) — Culver City, California
- Providence Facey Medical Foundation — Mission Hills, California
- Hoag Hospital — Newport Beach, California
- Paradigm Clinical Research Center, Inc. — Redding, California
- San Francisco VA — San Francisco, California
- Clinical Research of California LLC — Walnut Creek, California
- SCL Health Research Institute, St. Mary's — Grand Junction, Colorado
- Paradigm Clinical Research Center — Wheat Ridge, Colorado
- Stamford Health — Stamford, Connecticut
- Advanced Research — Boynton Beach, Florida
- Morton Plant Hospital — Clearwater, Florida
- SIMEDHealth, LLC — Gainesville, Florida
- Galenus Group — Lehigh Acres, Florida
- Renstar Medical Research — Ocala, Florida
- United Medical Research — Port Orange, Florida
- American Clinical Trials, LLC. — Acworth, Georgia
- Centricity Research Columbus Piedmont — Columbus, Georgia
- ClinCept, LLC — Columbus, Georgia
- Coastal Heritage Clinical Research — Hinesville, Georgia
- Centricity Research Gwinnett Pulmonology — Lawrenceville, Georgia
- Centricity Research Rincon Pulmonology — Rincon, Georgia
- OSF Saint Francis Medical Center — Peoria, Illinois
- Springfield Clinic — Springfield, Illinois
- St. Elizabeth Healthcare — Edgewood, Kentucky
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Lung Cancer
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- Early Detection of Lung Cancer — Nashville, Tennessee
- Improving Utilization of Lung Cancer Screening in Underserved PA Populations — Allentown, Pennsylvania
- Effect of Pulmonary Rehabilitation on Surgical Outcomes in the Cancer Setting — Houston, Texas
- Testing the Engaged Approach to Lung Cancer Screening — Denver, Colorado
- Real-Time Image Guided Lymphatic Mapping and Nodal Targeting in Lung Cancer — Boston, Massachusetts
Explore by condition: All Lung Cancer clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.