🏛️ Verified NIH Record • Updated 2026-08-27
A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease (NCT05347095)
A Phase 3, Randomized, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Janssen-Cilag Ltd.
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study to evaluate the clinical efficacy of guselkumab in fistulizing, perianal Crohn's disease and to assess the overall safety of guselkumab.
Who can join: Review the eligibility criteria below.
Location: University of Alabama at Birmingham — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (154 Sites)
Showing the first 25 of 154 sites.
- University of Alabama at Birmingham — Birmingham, Alabama
- Yale University — New Haven, Connecticut
- University of Miami — Miami, Florida
- Gastroenterology Group Of Naples — Naples, Florida
- AdventHealth Medical Group Blood & Marrow Transplant at Orlando — Orlando, Florida
- Kansas University Medical Center — Kansas City, Kansas
- University of Kentucky Chandler Medical Center — Lexington, Kentucky
- University of Louisville — Louisville, Kentucky
- Washington University School Of Medicine — St Louis, Missouri
- Mount Sinai School of Medicine — New York, New York
- Digestive Disease Specialists Inc — Oklahoma City, Oklahoma
- Gastro One — Germantown, Tennessee
- Vanderbilt University Medical Center — Nashville, Tennessee
- Tyler Research Institute, LLC — Tyler, Texas
- Swedish Medical Center — Seattle, Washington
- Flinders Medical Centre — Adelaide,
- St Vincent's Hospital - Melbourne — Fitzroy,
- Liverpool Hospital — Liverpool,
- Fiona Stanley Hospital — Murdoch,
- Royal Prince Alfred Hospital — Newtown,
- Royal Adelaide Hospital — North Terrace,
- Royal Melbourne Hospital — Parkville,
- Royal Perth Hospital — Perth,
- Mater Hospital — South Brisbane,
- Hopital Erasme — Brussels,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Fistulizing Crohns Disease clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.