Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth in/Near Infected Bone Cavities (NCT05361941)
🩺 Plain-English Summary (8th-Grade Level)
This is a pivotal, prospective, multi-center, randomized, concurrent control, patient and assessor-blinded study with two arms: a treatment arm (where subjects will be treated with the EP Granules + Tobramycin (EP G + T) investigational device, a combination device + antibiotic, in the 1st stage of a staged revision for periprosthetic joint infection (PJIs), and a control arm (where subjects are treated with the standard-of-care revision for infected PJIs).
Who can join: Review the eligibility criteria below.
Location: University of Southern California — Los Angeles, California
Age range: 22 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (16 Sites)
- University of Southern California — Los Angeles, California
- Georgetown University Medical Center — Washington D.C., District of Columbia
- Endeavor Health Skokie Hospital — Skokie, Illinois
- OrthoIndy — Indianapolis, Indiana
- Sinai Hospital — Baltimore, Maryland
- Massachusetts General Hospital — Boston, Massachusetts
- Brigham & Womens Hospital — Boston, Massachusetts
- U Michigan Medical Center — Ann Arbor, Michigan
- Hospital for Special Surgery — New York, New York
- OrthoCarolina — Charlotte, North Carolina
- Sanford South University Medical Center — Fargo, North Dakota
- JIS Orthopedics — Columbus, Ohio
- Carrollton regional Medical Center — Carrollton, Texas
- UT Health San Antonio — San Antonio, Texas
- Jordan Valley Medical Center — West Jordan, Utah
- West Virginia University Medical Center — Morgantown, West Virginia
📞 Contact the Study Coordinator
Phone: (801) 410-4330
Email: ak@elutinc.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Periprosthetic Joint Infections clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.