Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer (NCT05367440)
A Multi-arm, Open-label Phase I/IIa Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of AZD5305 in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer (PETRANHA)
๐ฉบ Plain-English Summary (8th-Grade Level)
This study will evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of AZD5305 when given in combination with new hormonal agents (NHAs) in patients with Metastatic Prostate Cancer.
Who can join: Review the eligibility criteria below.
Location: Research Site โ Detroit, Michigan
Age range: 18 Years to 130 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (20 Sites)
- Research Site โ Detroit, Michigan
- Research Site โ Detroit, Michigan
- Research Site โ Syracuse, New York
- Research Site โ Myrtle Beach, South Carolina
- Research Site โ Houston, Texas
- Research Site โ Houston, Texas
- Research Site โ Camperdown,
- Research Site โ Darlinghurst,
- Research Site โ East Melbourne,
- Research Site โ Heidelberg,
- Research Site โ Melbourne,
- Research Site โ St Leonards,
- Research Site โ Candiolo,
- Research Site โ Milan,
- Research Site โ Orbassano,
- Research Site โ Padova,
- Research Site โ Cambridge,
- Research Site โ Glasgow,
- Research Site โ Manchester,
- Research Site โ Plymouth,
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Metastatic Prostate Cancer
- Phase Ia/Ib Talazoparib + Tazemetostat for mCRPC โ Boston, Massachusetts
- PSMAtrack-tracking Changes in PSMA-PET During Initial Therapy for Metastatic Hormone-sensitive Prostate Cancer โ Boston, Massachusetts
- Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate Cancer โ Basking Ridge, New Jersey
- Prostate Cancer Monitoring Using [18F]DCFPyL and Blood Based Biomarkers โ New York, New York
- Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC โ Tucson, Arizona
Explore by condition: All Metastatic Prostate Cancer clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.