🏛️ Verified NIH Record • Updated 2026-04-07
Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB) (NCT05367609)
🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: Senthil Sadhasivam
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this collaborative CTSA application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in children undergoing painful surgery.
Who can join: Review the eligibility criteria below.
Location: University of California — San Francisco, California
Age range: 10 Years to 21 Years
🧪 Interventions in This Study
- Preoperative Genotyping (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (5 Sites)
- University of California — San Francisco, California
- Children's Orthopaedic and Scoliosis Surgery Associates, LLP — St. Petersburg, Florida
- Johns Hopkins All Children's Hospital — St. Petersburg, Florida
- Riley Children's Hospital — Indianapolis, Indiana
- UPMC Children's Hospital — Pittsburgh, Pennsylvania
📞 Contact the Study Coordinator
Phone: (412) 647-2994
Email: sadhasivams@upmc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All PPAP clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.