๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-08-29

A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma (NCT05372354)

An Exploratory Phase 1b/2a Multicenter, Open-Label, Novel-Novel Combination Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of CC-92480 (BMS-986348) in Novel Therapeutic Combinations in Participants With Relapsed or Refractory Multiple Myeloma

๐ŸŸข Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Bristol-Myers Squibb

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to assess the safety, tolerability and preliminary effectiveness of CC-92480 (BMS-986348) in novel therapeutic combinations for the treatment of Relapsed or Refractory Multiple Myeloma (RRMM).

Who can join: Review the eligibility criteria below.

Location: UAB Comprehensive Cancer Center โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (17 Sites)

  • UAB Comprehensive Cancer Center โ€” Birmingham, Alabama
  • Johns Hopkins Medicine - The Sidney Kimmel Comprehensive Cancer Center โ€” Baltimore, Maryland
  • Dana-Farber Cancer Institute โ€” Boston, Massachusetts
  • John Theurer Cancer Center at Hackensack UMC โ€” Hackensack, New Jersey
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • Alberta Health Services AHS - Foothills Medical Centre FMC โ€” Calgary, Alberta
  • University of Alberta - Cross Cancer Institute โ€” Edmonton, Alberta
  • University Health Network UHN - Princess Margaret Hospital PMH โ€” Toronto, Ontario
  • Oslo University Hospital โ€” Oslo, Outside US and Canada
  • ICO - Hospital Germans Trias i Pujol โ€” Barcelona,
  • Hospital Universitario 12 de Octubre โ€” Madrid,
  • Hospital Universitario Marques de Valdecilla โ€” Santander,
  • The Christie NHS Foundation Trust โ€” Manchester, Greater Manchester
  • Local Institution - 0001 โ€” Leicester, Leicestershire
  • Local Institution - 0014 โ€” Liverpool, Merseyside
  • Churchill Hospital โ€” Oxford, Oxfordshire
  • NIHR UCLH Clinical Research Facility โ€” London,

๐Ÿ“ž Contact the Study Coordinator

Phone: (855) 907-3286

Email: Clinical.Trials@bms.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Multiple Myeloma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—