๐๏ธ Verified NIH Record โข Updated 2026-05-12
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS (NCT05379985)
A Multicenter Open-Label Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
๐ข Recruiting Phase1 / Phase2 ๐ Investigational Drug / Biologic Sponsor: Revolution Medicines, Inc.
๐ฉบ Plain-English Summary (8th-Grade Level)
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.
Who can join: Review the eligibility criteria below.
Location: UC Irvine/Chao Family Comprehensive Cancer Center โ Orange, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (21 Sites)
- UC Irvine/Chao Family Comprehensive Cancer Center โ Orange, California
- UCLA โ Santa Monica, California
- Moffitt Cancer Center โ Tampa, Florida
- Piedmont Healthcare โ Atlanta, Georgia
- Mary Bird Perkins Cancer Center โ Baton Rouge, Louisiana
- Johns Hopkins University โ Baltimore, Maryland
- Dana Farber Cancer Institute โ Boston, Massachusetts
- Perlmutter Cancer Center at NYU Langone Health โ New York, New York
- Memorial Sloan-Kettering Cancer Center โ New York, New York
- Columbia University โ New York, New York
- Christ Hospital Cancer Center โ Cincinnati, Ohio
- Taylor Cancer Research Center โ Maumee, Ohio
- Tennessee Oncology โ Chattanooga, Tennessee
- Sarah Cannon Research Institute โ Nashville, Tennessee
- University of Texas at Austin โ Austin, Texas
- Mary Crowley Cancer Research โ Dallas, Texas
- The University of Texas MD Anderson Cancer Center โ Houston, Texas
- Next Oncology โ San Antonio, Texas
- Huntsman Cancer Institute โ Salt Lake City, Utah
- Next Oncology Virginia โ Fairfax, Virginia
- Virginia Mason Medical Center โ Seattle, Washington
๐ Contact the Study Coordinator
Phone: (844) 273-8633
Email: medinfo@revmed.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.