🏛️ Verified NIH Record • Updated 2026-04-27
Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder (NCT05396638)
Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents
🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program Sponsor: University of Colorado, Denver
🩺 Plain-English Summary (8th-Grade Level)
This project seeks to learn more about the effects of cannabis use on the endocannabinoid system and endogenous opioid systems in adolescents to address a fundamental gap in knowledge and identify biomarkers that may help distinguish youth who relapse from youth who remain sober.
Who can join: Review the eligibility criteria below.
Location: University of Colorado Anschutz Medical Campus — Aurora, Colorado
Age range: 14 Years to 25 Years
🧪 Interventions in This Study
- Contingency Management (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Colorado Anschutz Medical Campus — Aurora, Colorado
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cannabis Use
- Feasibility/Acceptability of a Brief Motivational Intervention for Frequent/High-Intensity Cannabis Use — Seattle, Washington
- Acute Effects of Cannabis on Cognition and Affect — Pullman, Washington
- Research Investigating Drug Effects-2 (RiDE-2) — Chicago, Illinois
- Smart Talk: Cannabis Awareness and Prevention Curriculum Evaluation — Palo Alto, California
- Lung Health and Breath Biomarkers: Acute Effects of Inhaled Cannabis — Lexington, Kentucky
Explore by condition: All Cannabis Use clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.