Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age (NCT05422222)

🧪 Interventions in This Study

• VX-121/TEZ/D-IVA (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (38 Sites)

Showing the first 25 of 38 sites.

• Children's Hospital of Orange County — Orange, California
• Stanford University Clinical and Translational Research Unit — Palo Alto, California
• Children's Hospital of Colorado — Aurora, Colorado
• The Emory Clinic / Children's Healthcare of Atlanta at Egleston — Atlanta, Georgia
• Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois
• Riley Hospital for Children at Indiana University Health — Indianapolis, Indiana
• Boston Children's Hospital — Boston, Massachusetts
• Children's Respiratory and Critical Care Specialists, P.A., Children's Hospitals and Clinics of Minnesota — Minneapolis, Minnesota
• The Children's Mercy Hospital — Kansas City, Missouri
• Washington University School of Medicine / St. Louis Children's Hospital — St Louis, Missouri
• Cohen Children's Medical Center — Lake Success, New York
• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio
• Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center — Cleveland, Ohio
• Nationwide Children's Hospital — Columbus, Ohio
• Oregon Health & Science University — Portland, Oregon
• UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania
• Texas Children's Hospital - Wallace Tower — Houston, Texas
• Vermont Lung Center — Colchester, Vermont
• American Family Childrens Hospital — Madison, Wisconsin
• The Kids Research Institute Australia — Nedlands,
• Women's and Children's Hospital — North Adelaide,
• The Royal Children's Hospital — Parkville,
• Queensland Children's Hospital — South Brisbane,
• The Hospital for Sick Children — Toronto,
• British Columbia Children's Hospital — Vancouver,

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Cystic Fibrosis

• Genetic Modifiers of Cystic Fibrosis (CF) Liver Disease — Chapel Hill, North Carolina
• Hyperpolarized Imaging for New Treatments — Cincinnati, Ohio
• Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRI — Cincinnati, Ohio
• Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older — Nedlands,
• Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis — Cincinnati, Ohio

Explore by condition: All Cystic Fibrosis clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Review the official NIH record below to find the coordinating site.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.