🏛️ Verified NIH Record • Updated 2024-10-29

The DRAGON 2 Trial (NCT05428735)

An International Multicenter Randomized Controlled Trial to Compare Combined Portal and Hepatic Vein Embolization (PVE/HVE) with PVE Alone in Patients with Colorectal Liver Cancer Metastases (CRLM) and a Small Future Liver Remnant (FLR)

🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol Sponsor: Maastricht University

🩺 Plain-English Summary (8th-Grade Level)

In the randomized controlled DRAGON 2 trial study subjects will be randomized between two arms, PVE alone (control group) and PVE/HVE (interventional group).

Who can join: Review the eligibility criteria below.

Location: Yale New Haven Hospital — New Haven, Connecticut

Age range: 18 Years

🧪 Interventions in This Study

  • Embolization (PROCEDURE)

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (24 Sites)

  • Yale New Haven Hospital — New Haven, Connecticut
  • Monash Medical Centre — Clayton, Victoria
  • Social Medical Center, South — Vienna, State of Vienna
  • Hôpital Erasme — Brussels, Brussels Capital
  • CHU de Liège — Liège, Liège
  • CHU-UCL Namur site Godinne — Yvoir, Namen
  • UZ Gent — Ghent, Oost-Vlaanderen
  • Vancouver Coastal Health — Vancouver, British Columbia
  • Juravinski Hospital and Cancer Centre — Hamilton, Ontario
  • The Ottawa Hospital — Ottawa, Ontario
  • Sunnybrook Hospital — Toronto, Ontario
  • McGill University Health Center — Montreal,
  • IRCCS San Raffaele Hospital — Milan,
  • Maastricht University Medical Center+ — Maastricht, Limburg
  • Amsterdam UMC, location AMC — Amsterdam, North Holland
  • University Medical Center Groningen — Groningen, Provincie Groningen
  • Erasmus Medical Center — Rotterdam, South Holland
  • Amphia — Breda,
  • Maxima Medisch Centrum — Eindhoven,
  • Universitair Medisch Centrum Utrecht — Utrecht,
  • Linköping University Hospital — Linköping,
  • Karolinska University Hospital — Stockholm,
  • Claraspital & Clarunis University Hospital Basel — Basel, Canton of Basel-City
  • Kantonsspital Winterthur (KSW) — Winterthur,

📞 Contact the Study Coordinator

Phone: +31 638463945

Email: sinead.james@mumc.nl

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗