🏛️ Verified NIH Record • Updated 2026-01-22
Single Visit Clinical Validation of ScreenFire, a Low-cost HPV Test (NCT05431699)
SCALE: Single Visit Clinical Validation of ScreenFire, a Low-cost HPV Test: Efficacy and Cost Effectiveness
🔵 Active, Not Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol Sponsor: The Cleveland Clinic
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to validate a new low-cost, self-collected HPV screening test (ScreenFire) and compare it to the standard provider collected careHPV, for the detection of high grade cervical cancer.
Who can join: Review the eligibility criteria below.
Location: Ministerio de Salud — San Salvador
Age range: 30 Years to 59 Years
🧪 Interventions in This Study
- ScreenFire HPV test (DIAGNOSTIC_TEST)
- careHPV test (DIAGNOSTIC_TEST)
- Colposcopy and biopsy (PROCEDURE)
- Gas-based cryotherapy (PROCEDURE)
- Thermal ablation (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Ministerio de Salud — San Salvador,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Human Papilloma Virus
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- Advancing HPV Vaccination Among HIV Positive Adults: The CHAMPS Study — Albany, Georgia
- Impact of Standing Orders Optimization — Chapel Hill, North Carolina
- Immunogenicity of the 9vHPV Vaccination 2-dose Regimen Among Children 4 to 8 Years Old — Boston, Massachusetts
- Impact of Financial Incentives — Chapel Hill, North Carolina
Explore by condition: All Human Papilloma Virus clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.