๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-12-05

A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes (NCT05433584)

A Randomized, Open-Label, Parallel-Group, Two-Arm, Phase 4 Study to Evaluate the Long-Term Efficacy and Safety of Tirzepatide Compared With Intensified Conventional Care in Adults When Initiating Treatment Early in the Course of Type 2 Diabetes

๐Ÿ”ต Active, Not Recruiting Phase4 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Eli Lilly and Company

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study aims to investigate the efficacy and safety of tirzepatide in participants with type 2 diabetes (T2D) compared to other existing treatment options when treatment is initiated early.

Who can join: Review the eligibility criteria below.

Location: Cahaba Research - Trussville โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (90 Sites)

Showing the first 25 of 90 sites.

  • Cahaba Research - Trussville โ€” Birmingham, Alabama
  • San Fernando Valley Health Institute โ€” Canoga Park, California
  • Velocity Clinical Research, Huntington Park โ€” Huntington Park, California
  • Velocity Clinical Research, San Diego โ€” La Mesa, California
  • Clinical Trials Research โ€” Lincoln, California
  • Velocity Clinical Research, Westlake โ€” Los Angeles, California
  • Catalina Research Institute, LLC โ€” Montclair, California
  • Velocity Clinical Research, North Hollywood โ€” North Hollywood, California
  • Velocity Clinical Research, Panorama City โ€” Panorama City, California
  • Western University of Health Sciences โ€” Pomona, California
  • Velocity Clinical Research, Santa Ana โ€” Santa Ana, California
  • New England Research Associates, LLC โ€” Bridgeport, Connecticut
  • Excel Medical Clinical Trials โ€” Boca Raton, Florida
  • Alliance for Multispecialty Research, LLC โ€” Coral Gables, Florida
  • South Florida Clinical Research Institute โ€” Margate, Florida
  • Emory University School of Medicine- Grady Campus โ€” Atlanta, Georgia
  • Center for Advanced Research & Education โ€” Gainesville, Georgia
  • Qualmedica Research, LLC โ€” Evansville, Indiana
  • Iowa Diabetes and Endocrinology Research Center โ€” West Des Moines, Iowa
  • Qualmedica Research โ€” Bowling Green, Kentucky
  • NECCR PrimaCare Research โ€” Fall River, Massachusetts
  • SKY Integrative Medical Center/SKYCRNG โ€” Ridgeland, Mississippi
  • StudyMetrix Research โ€” City of Saint Peters, Missouri
  • Clinvest Research LLC โ€” Springfield, Missouri
  • Research Foundation of SUNY - University of Buffalo โ€” Buffalo, New York

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Type 2 Diabetes clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—