Coconut Oil to Prevent Mouth Sores in Pediatric Patients Receiving High Dose Chemotherapy (NCT05441813)
A Randomized, Open-label Study of Coconut Oil Mouth Rinse for Prophylaxis of Severe Oral Mucositis in Pediatric Patients Receiving Myeloablative Conditioning Regimens
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to learn if virgin coconut oil (VCO) mouth rinse can help prevent oral mucositis. The Study Investigator will compare standard of care mucositis prevention rinses with the VCO mouth rinse added to the standard of care mucositis prevention rinses. The severity of oral mucositis between the 2 groups will be evaluated. Some of the standard of care rinses that can be used to prevent mucositis are normal saline, Benadryl (diphenhydramine), Mylanta, lidocaine, or other combinations.
Who can join: Review the eligibility criteria below.
Location: Atrium Health Levine Children's Hospital — Charlotte, North Carolina
Age range: 7 Years to 26 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Atrium Health Levine Children's Hospital — Charlotte, North Carolina
📞 Contact the Study Coordinator
Phone: (980) 442-2323
Email: sceria.jenkins@advocatehealth.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Oral Mucositis
- Photobiomodulation for the Prevention of Oral Mucositis — Boston, Massachusetts
- RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer — Gilbert, Arizona
- F.L.O.S.S. Project (Facilitated Lessons on Oral and Systemic Health in Survivors) — Washington D.C., District of Columbia
Explore by condition: All Oral Mucositis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.