πŸ›οΈ Verified NIH Record β€’ Updated 2026-07-31

Gastrointestinal Dysmotility on Aspiration Risk (NCT05455359)

The Impact of Upper Gastrointestinal Dysmotility on Aspiration-associated Symptoms

🟒 Recruiting Phase4 πŸ’Š Investigational Drug / Biologic Sponsor: Boston Children's Hospital

🩺 Plain-English Summary (8th-Grade Level)

The hypothesis of this study is that esophageal and gastric dysmotility increase the risk of developing aspiration-associated symptoms in children with neurologic impairment. The investigators are conducting a ten week cross over study comparing prucalopride to famotidine for the treatment of aspiration-associated symptoms.

Who can join: Review the eligibility criteria below.

Location: Boston Children's Hospital β€” Boston, Massachusetts

Age range: 5 Years to 21 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (1 Sites)

  • Boston Children's Hospital β€” Boston, Massachusetts

πŸ“ž Contact the Study Coordinator

Phone: (617) 355-0897

Email: rachel.rosen@childrens.harvard.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—