Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes (NCT05482789)
Pilot Study of Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes
🩺 Plain-English Summary (8th-Grade Level)
This study is being done to study how exenatide, an FDA-approved drug that lowers blood sugar in non-pregnant patients with type II diabetes, works in pregnant women. To do this, the investigators will study the drug's pharmacokinetics (what the body does to the drug; specifically, how quickly your body breaks down and excretes exenatide) and pharmacodynamics (what the drug does to the body; specifically, how effectively exenatide helps the participants' pancreas secrete insulin and how well it controls blood sugar after a meal). There are only two main drug therapies (insulin injections and glyburide pills) currently used for gestational diabetes and not all women achieve good enough blood sugar control without side effects. Therefore, the investigators hope to find out if exenatide might also be helpful in gestational diabetes.
Who can join: Review the eligibility criteria below.
Location: Magee Womens Hospital of UPMC — Pittsburgh, Pennsylvania
Age range: 18 Years to 50 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Magee Womens Hospital of UPMC — Pittsburgh, Pennsylvania
📞 Contact the Study Coordinator
Phone: (412) 647-1000
Email: feghalim@upmc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Gestational Diabetes
- Preventing Obstetric Complications With Dietary Intervention — Milwaukee, Wisconsin
- Healthy Eating in Women at Risk of Gestational Diabetes — Québec, Quebec
- Role of Adipokines in Glucose Regulation During Pregnancy and in Fetal Development — Sherbrooke, Quebec
- Predicting Dysglycemia in Individuals With Gestational Diabetes Immediately Postpartum Using Continuous Glucose Monitoring — Calgary, Alberta
- Role of NADPH Oxidase in Microvascular Dysfunction Following GDM — Iowa City, Iowa
- Gestational Diabetes and Pharmacotherapy (GAP) — Milwaukee, Wisconsin
Explore by condition: All Gestational Diabetes clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.