Treatment for Antepartum Posttraumatic Stress Disorder/PTSD Study (NCT05486793)
A Non-Inferiority Trial Testing Delivery of Written Exposure Therapy by Community Health Workers For Treatment of PTSD During Pregnancy
🩺 Plain-English Summary (8th-Grade Level)
The majority of women with perinatal posttraumatic stress disorder (PTSD) do not receive mental health treatment despite the documented associations between PTSD and adverse pregnancy outcomes; this is likely due to workforce shortages, lack of data on the effectiveness of existing evidence-based treatment for PTSD in usual care obstetrics settings, and patient-level barriers to engagement such as stigma. The proposed study is a randomized controlled trial, which will examine the effectiveness of a brief evidence-based treatment for PTSD (i.e., Written Exposure Therapy) during pregnancy and the non-inferiority of delivery of this treatment by community health workers vs. delivery by mental health clinicians.
Who can join: Review the eligibility criteria below.
Location: Boston Medical Center and remote — Boston, Massachusetts
Age range: 18 Years to 50 Years
🧪 Interventions in This Study
- Written Exposure Therapy (WET) (BEHAVIORAL)
- Emotion Focused Supportive Therapy (EFST) (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Boston Medical Center and remote — Boston, Massachusetts
📞 Contact the Study Coordinator
Phone: (781) 413-6319
Email: yael.nillni@bmc.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in PTSD
- Circadian Influence on Prolonged Exposure Therapy for PTSD — Boston, Massachusetts
- Safety and Preliminary Efficacy of Organic Whole Psilocybin-Containing Mushrooms to Treat Patients Suffering From PTSD — Scottsdale, Arizona
- Non-Inferiority Trial of TrIGR for PTSD — San Diego, California
- Utility of Brexanolone to Target Stress-induced Alcohol Use Among Men and Women With Posttraumatic Stress Disorder — New Haven, Connecticut
- Non-invasive Nerve Stimulation and Sleep — Gainesville, Florida
- A Deployment Focused Pragmatic Trial of Optimal Stepped Care Intervention Targeting PTSD and Comorbidity for Acutely Hospitalized Injury Survivors Treated in US Trauma Care Systems — Seattle, Washington
Explore by condition: All PTSD clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.