🏛️ Verified NIH Record • Updated 2026-07-06
Study of Cabozantinib and Nivolumab in Metastatic Castration Resistant Prostate Cancer (NCT05502315)
A Phase 2 Study of Cabozantinib and Nivolumab in Metastatic Castration Resistant Prostate Cancer
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Rana McKay, MD
🩺 Plain-English Summary (8th-Grade Level)
This is a multicenter, single-arm, two-stage open-label phase 2 study of the combination of cabozantinib + nivolumab in subjects with advanced castration-resistant prostate cancer (CRPC).
Who can join: Review the eligibility criteria below.
Location: University of California San Diego — La Jolla, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (4 Sites)
- University of California San Diego — La Jolla, California
- University of Chicago Medical Center — Chicago, Illinois
- University of Texas Southwestern Medical Center — Dallas, Texas
- University of Wisconsin — Madison, Wisconsin
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Castration-resistant Prostate Cancer
- pTVG-HP DNA Vaccine With or Without pTVG-AR DNA Vaccine and Pembrolizumab in Patients With Castration-Resistant, Metastatic Prostate Cancer — St Louis, Missouri
- Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer — Duarte, California
- GZ17-6.02 in Advanced CRPC After Progression on Anti-Androgen Therapy — Richmond, Virginia
Explore by condition: All Castration-resistant Prostate Cancer clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.