๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-01-21

The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer (NCT05502523)

The Impact of Surgical Technique on Circulating Tumor DNA in Early-Stage Non-Small Cell Lung Cancer

๐ŸŸข Recruiting Observational / Diagnostic ๐Ÿฉบ Clinical Procedure Protocol Sponsor: Thomas Jefferson University

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This clinical trial compares the effect of pulmonary vein-first surgical technique to pulmonary artery-first surgical technique in decreasing circulating tumor cell deoxyribonucleic acid (ctDNA) in patients with stage I-III non-small cell lung cancer. Pulmonary vein first and pulmonary artery first surgical techniques are standard surgical techniques for the division of the blood vessels during lung resection surgery. Pulmonary vein-first surgical technique may reduce the risk of shedding tumor cells during surgery and influence long term overall survival.

Who can join: Review the eligibility criteria below.

Location: Abington Memorial Hospital โ€” Abington, Pennsylvania

Age range: 18 Years

๐Ÿงช Interventions in This Study

  • Pulmonary Artery-First Surgical Technique (PROCEDURE)
  • Biospecimen Collection (PROCEDURE)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (4 Sites)

  • Abington Memorial Hospital โ€” Abington, Pennsylvania
  • Jefferson Health Northeast โ€” Philadelphia, Pennsylvania
  • Thomas Jefferson University Hospital โ€” Philadelphia, Pennsylvania
  • Asplundh Cancer Pavilion at Jefferson Health โ€” Willow Grove, Pennsylvania

๐Ÿ“ž Contact the Study Coordinator

Phone: (215) 955-5562

Email: Tyler.grenda@jefferson.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—