Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application (NCT05506085)
🩺 Plain-English Summary (8th-Grade Level)
Deep Brain Stimulation (DBS) is a neurosurgical procedure used to treat tremors, and dystonia. This study will enroll people who have a form of focal dystonia that affects their vocal cords called Adductor Laryngeal dystonia (ADLD). Participants will undergo Deep Brain Stimulation surgery to treat laryngeal dystonia as part of their clinical care. Before surgery, as part of the study they will have specialized testing to study the movement of the vocal cords, as well as functional magnetic resonance imaging (fMRI). While in the operating room, researchers will examine brain waves to better understand how faulty brain firing patterns lead to dystonia. After surgery, and activation of the deep brain stimulator, participants will repeat speech testing and vocal cord imaging as well as magnetic resonance imaging (MRI).
Who can join: Review the eligibility criteria below.
Location: Indiana University — Indianapolis, Indiana
Age range: 18 Years to 70 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Indiana University — Indianapolis, Indiana
📞 Contact the Study Coordinator
Phone: (812) 855-3886
Email: patelrir@iu.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Laryngeal Dystonia
- Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor — Boston, Massachusetts
- Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor — Boston, Massachusetts
- Brain-Computer Interfaces in Laryngeal Dystonia — Boston, Massachusetts
- Effects of Neuromodulation in Laryngeal Dystonia — Boston, Massachusetts
- Imaging Genetics of Laryngeal Dystonia — Boston, Massachusetts
- tDCS for Laryngeal Dystonia — New Haven, Connecticut
Explore by condition: All Laryngeal Dystonia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.