Low Dose Aspirin for Preterm Preeclampsia Preventionmg/day Dose in High-risk Patients (NCT05514847)
Low Dose Aspirin for Preterm Preeclampsia Prevention - a Randomized Trial of 81 Vs 162 Mg/day Dose in High-risk Patients
🩺 Plain-English Summary (8th-Grade Level)
This will be a randomized, open-label, controlled trial of patients at high risk of developing preeclampsia examining 81 mg/day vs 162mg/day daily acetylsalicylic acid (ASA) use. Based on screening results, patients will be randomized as outlined below into one of four groups. The proposed study is a pilot to determine if the higher dose of ASA has positive impacts on measures that predict preeclampsia, compared to the lower dose. If positive findings, data from this study could be used to develop a larger trial powered to determine if the higher ASA dose can improve clinical outcomes.
Who can join: Review the eligibility criteria below.
Location: University of Virginia — Charlottesville, Virginia
Age range: 18 Years to 45 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Virginia — Charlottesville, Virginia
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Preeclampsia
- Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial — Pittsburgh, Pennsylvania
- Preeclampsia Postpartum Antihypertensive Treatment — Milwaukee, Wisconsin
- Preeclampsia Educational Program Study (PrEPS) — Long Beach, California
- MR and Inflammation After Preeclampsia — Iowa City, Iowa
- Clinician Notification to Increase Aspirin Prophylaxis for Preeclampsia Prevention — Boston, Massachusetts
Explore by condition: All Preeclampsia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.