The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial (NCT05523479)
🩺 Plain-English Summary (8th-Grade Level)
The METEOR Trial will compare four implementation strategies-traditional online education, protocol-directed care, interprofessional education, and a combination of protocol-directed care and interprofessional education-to test the hypotheses that interprofessional education is superior to traditional online education as an implementation strategy in the intensive care unit (ICU) and the benefits of interprofessional education are increased when interprofessional education is paired with a clinical protocol. Additionally, the trial will also test the hypothesis that preventive post-extubation NIV for high-risk patients and preventive post-extubation HFNC for low-risk patients are both superior to current clinical practice (i.e., conventional post-extubation oxygen therapy).
Who can join: Review the eligibility criteria below.
Location: UPMC Carlisle — Carlisle, Pennsylvania
Age range: 18 Years
🧪 Interventions in This Study
- Traditional online education (BEHAVIORAL)
- Interprofessional education (BEHAVIORAL)
- Clinical protocol (BEHAVIORAL)
- Risk-stratified preventive post-extubation noninvasive ventilation (NIV) or high-flow nasal cannula oxygen (HFNC) (OTHER)
- Preventive post-extubation high-flow nasal cannula oxygen (HFNC) (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (17 Sites)
- UPMC Carlisle — Carlisle, Pennsylvania
- UPMC Hanover — Hanover, Pennsylvania
- UPMC Harrisburg — Harrisburg, Pennsylvania
- UPMC Community Osteopathic — Harrisburg, Pennsylvania
- UPMC West Shore — Mechanicsburg, Pennsylvania
- UPMC East — Monroeville, Pennsylvania
- UPMC Jameson — New Castle, Pennsylvania
- University of Pittsburgh — Pittsburgh, Pennsylvania
- UPMC Magee-Womens Hospital — Pittsburgh, Pennsylvania
- UPMC Presbyterian — Pittsburgh, Pennsylvania
- UPMC St. Margaret — Pittsburgh, Pennsylvania
- UPMC Mercy — Pittsburgh, Pennsylvania
- UPMC Shadyside — Pittsburgh, Pennsylvania
- UPMC Passavant — Pittsburgh, Pennsylvania
- UPMC Northwest — Seneca, Pennsylvania
- UPMC Williamsport — Williamsport, Pennsylvania
- UPMC Memorial — York, Pennsylvania
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.