🏛️ Verified NIH Record • Updated 2026-05-19
Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve (NCT05526560)
A Prospective, Global Study Designed to Collect Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve
🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Edwards Lifesciences
🩺 Plain-English Summary (8th-Grade Level)
Collect real-world data on acute and long-term safety and performance of the MITRIS RESILIA Mitral Valve, Model 11400M, in subjects requiring replacement of their native or prosthetic mitral valve with or without concomitant procedures.
Who can join: Review the eligibility criteria below.
Location: Hoag Memorial Hospital Presbyterian — Newport Beach, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (34 Sites)
Showing the first 25 of 34 sites.
- Hoag Memorial Hospital Presbyterian — Newport Beach, California
- Stanford University — Palo Alto, California
- AdventHealth Orlando — Orlando, Florida
- Piedmont Heart Institute — Athens, Georgia
- Piedmont Heart Institute — Atlanta, Georgia
- Ascension St. Vincent Heart Center — Carmel, Indiana
- University of Michigan — Ann Arbor, Michigan
- Mayo Clinic, Rochester — Rochester, Minnesota
- Washington University Barnes-Jewish Hospital — St Louis, Missouri
- Mount Sinai Hospital — New York, New York
- Columbia University Irving Medical Center — New York, New York
- Weill Cornell Medicine — New York, New York
- Duke University Medical Center — Durham, North Carolina
- Hospital of the University of Pennsylvania — Philadelphia, Pennsylvania
- Allegheny General Hospital — Pittsburgh, Pennsylvania
- UPMC Presbyterian Shadyside — Pittsburgh, Pennsylvania
- Tristar Centennial Medical Center — Nashville, Tennessee
- Ascension Saint Thomas — Nashville, Tennessee
- University of Utah — Salt Lake City, Utah
- Aurora St. Luke's Medical Center — Milwaukee, Wisconsin
- St. Paul's Hospital and Vancouver General Hospital — Vancouver, British Columbia
- London Health Sciences Centre, University Hospital (LHSC) — London, Ontario
- Montreal Heart Institute — Montreal, Quebec
- Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval — Québec,
- Universitätsklinikum Augsburg — Augsburg,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Mitral Stenosis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.