A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease (NCT05531656)
Synaptic Therapy Alzheimer's Research Trial (START): A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease Over 18 Months.
🩺 Plain-English Summary (8th-Grade Level)
This is a multicenter randomized, double-blind, placebo-controlled Phase 2 study designed to evaluate the efficacy, safety, and tolerability of two doses of CT1812 compared to placebo in participants diagnosed with early Alzheimer's disease.
Who can join: Review the eligibility criteria below.
Location: University of Alabama at Birmingham — Birmingham, Alabama
Age range: 50 Years to 85 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (50 Sites)
Showing the first 25 of 50 sites.
- University of Alabama at Birmingham — Birmingham, Alabama
- Banner Alzheimer's Institute — Phoenix, Arizona
- Banner Sun Health Research Institute — Sun City, Arizona
- University of California — Irvine, California
- Stanford University — Palo Alto, California
- Sutter Institute for Medical Research — Sacramento, California
- Yale University — New Haven, Connecticut
- Georgetown University — Washington D.C., District of Columbia
- Howard University — Washington D.C., District of Columbia
- Brain Matters Research — Delray Beach, Florida
- Neuropsychiatric Research Center of Southwest Florida — Fort Myers, Florida
- Mayo Clinic,Jacksonville — Jacksonville, Florida
- JEM Research Institute — Lake Worth, Florida
- K2 Medical Research, LLC — Maitland, Florida
- Advanced Clinical Research Network, Corp — Miami, Florida
- Charter Research — Orlando, Florida
- Headlands Research Orlando — Orlando, Florida
- Brain Matters Research Stuart — Stuart, Florida
- University of South Florida — Tampa, Florida
- Conquest Research, LLC — Winter Park, Florida
- Rush University Medical Center — Chicago, Illinois
- Indiana University — Indianapolis, Indiana
- Sanders-Brown Center on Aging — Lexington, Kentucky
- John Hopkins University — Baltimore, Maryland
- Brigham and Women's Hospital — Boston, Massachusetts
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.