🏛️ Verified NIH Record • Updated 2026-08-04

A Study Evaluating the Efficacy and Safety of Cevostamab in Prior B Cell Maturation Antigen (BCMA)-Exposed Participants With Relapsed/Refractory Multiple Myeloma (NCT05535244)

A Phase I/II, Open-Label, Multi-Cohort Study to Evaluate the Efficacy and Safety of Cevostamab in Prior B Cell Maturation Antigen-Exposed Patients With Relapsed/Refractory Multiple Myeloma

🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic Sponsor: Hoffmann-La Roche

🩺 Plain-English Summary (8th-Grade Level)

This study will evaluate the efficacy, safety, and pharmacokinetics of cevostamab in participants with relapsed or refractory multiple myeloma (R/R MM) via intravenous (IV) infusion.

Who can join: Review the eligibility criteria below.

Location: University of Colorado — Aurora, Colorado

Age range: 18 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (27 Sites)

Showing the first 25 of 27 sites.

  • University of Colorado — Aurora, Colorado
  • Mayo Clinic-Jacksonville — Jacksonville, Florida
  • University of Maryland Greenebaum Cancer Center — Baltimore, Maryland
  • Dana Farber Cancer Institute — Boston, Massachusetts
  • Mayo Clinic - Rochester — Rochester, Minnesota
  • Icahn School of Medicine at Mount Sinai (ISMMS) — New York, New York
  • Memorial Sloan Kettering Cancer Center — New York, New York
  • Tennessee Oncology - Nashville — Nashville, Tennessee
  • Hunstman Cancer Institute — Salt Lake City, Utah
  • Calvary Mater Newcastle — Waratah, New South Wales
  • St Vincent's Hospital Melbourne — Fitzroy, Victoria
  • UZ Leuven Gasthuisberg — Leuven,
  • CHU NANTES - Hôtel Dieu — Nantes,
  • APHP - Hospital Saint Louis — Paris,
  • CHU de Poitiers - La Miletrie — Poitiers,
  • Klinik der Uni zu Köln — Cologne,
  • Universitätsklinikum Hamburg-Eppendorf Onkologisches Zentrum Medizinische Klinik II — Hamburg,
  • Universitätsklinikum Würzburg — Würzburg,
  • Hadassah Ein Karem Hospital — Jerusalem,
  • Sheba Medical Center — Ramat Gan,
  • Sourasky Medical Centre — Tel Aviv,
  • Policlinico S.Orsola-Malpighi — Bologna, Emilia-Romagna
  • Asst Papa Giovanni Xxiii — Bergamo, Lombardy
  • Fond. IRCCS Istituto Nazionale Tumori — Milan, Lombardy
  • A.O. Città della Salute e della Scienza D - Osp. S. Giov. Battista Molinette — Turin, Piedmont

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Multiple Myeloma clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗