The COVID-19 VaccinE Response and Co-Administration in Rheumatology Patients (COVER-CoAd) (NCT05543642)
The COvid19 VaccinE Response and Co-Administration in Rheumatology Patients (COVER-CoAd)
🩺 Plain-English Summary (8th-Grade Level)
Based on the experience with influenza, pneumococcal, and shingles vaccinations in rheumatic disease populations, it is clear that some disease modifying anti-rheumatic drugs and the immunomodulatory therapies used to treat immune-mediated inflammatory diseases have the capacity to blunt immune responses to COVID-19 vaccines. Several studies have suggested that patients with autoimmune conditions may be at increased risk of poor COVID-19 outcomes. There is an urgent need to better clarify the immunogenicity and safety of COVID-19 vaccines in people living with rheumatic disease who use immunomodulatory therapies. Boosters at annual or other frequency are available, and there is a need to understand whether these vaccines can be given concurrently with other routine vaccines.
Who can join: Review the eligibility criteria below.
Location: Center for Rheumatic Diseases — Northport, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (7 Sites)
- Center for Rheumatic Diseases — Northport, Alabama
- Southwest Florida Rheumatology — Riverview, Florida
- St. Luke's Rheumatology — Boise, Idaho
- Jayashree Sinha, MD — Clovis, New Mexico
- Oregon Health & Science University — Portland, Oregon
- Altoona Center for Clinical Research — Duncansville, Pennsylvania
- Cumberland Rheumatology — Crossville, Tennessee
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Rheumatic Diseases
- Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases — Chicago, Illinois
- Personalized Outreach for Equitable Treatment in Rheumatology — Vancouver, British Columbia
- Rheumatology Patient Registry and Biorepository — New Haven, Connecticut
- The RheumSafer Study: Improving Medication Appropriateness in People With Rheumatic Conditions — Montreal, Quebec
- Studies of the Natural History of Rheumatic Diseases — Bethesda, Maryland
Explore by condition: All Rheumatic Diseases clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.