🏛️ Verified NIH Record • Updated 2026-05-25

Evaluating XPERIENCE™ Advanced Surgical Irrigation (NCT05543941)

Evaluating XPERIENCE™ Advanced Surgical Irrigation on Risk of Periprosthetic Joint Infection: A Multicenter Randomized Controlled Trial

🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: Ottawa Hospital Research Institute

🩺 Plain-English Summary (8th-Grade Level)

A prospective, multi-center, double-arm, parallel, interventional, randomized, controlled clinical trial to assess the rate of periprosthetic joint infection (PJI) in patients undergoing primary total knee arthroplasty (TKA), total hip arthroplasty (THA) or hip resurfacing (HR) with XPERIENCE™ (XP) Advanced Surgical Irrigation versus dilute Betadine (DB).

Who can join: Review the eligibility criteria below.

Location: University of British Columbia — Vancouver, British Columbia

Age range: 18 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (8 Sites)

  • University of British Columbia — Vancouver, British Columbia
  • London Health Sciences Center — London, Ontario
  • The Ottawa Hospital — Ottawa, Ontario
  • Humber River Health — Toronto, Ontario
  • St. Joseph's Health Centre — Toronto, Ontario
  • Hôpital Maisonneuve-Rosemont — Montreal, Quebec
  • Jewish General Hospital — Montreal, Quebec
  • CHU de Quebec-Université Laval — Québec, Quebec

📞 Contact the Study Coordinator

Phone: (613) 737-8899

Email: scosta@ohri.ca

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗