๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-19

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma (NCT05548296)

A Phase 2 Study of ACR-368 Therapy in Subjects With Endometrial Cancer

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Acrivon Therapeutics

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitization in participants with endometrial cancer.

Who can join: Review the eligibility criteria below.

Location: University of South Alabama Mitchell Cancer Institute โ€” Mobile, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (90 Sites)

Showing the first 25 of 90 sites.

  • University of South Alabama Mitchell Cancer Institute โ€” Mobile, Alabama
  • Alaska Women's Cancer Center โ€” Anchorage, Alaska
  • HonorHealth โ€” Phoenix, Arizona
  • Arizona Oncology Associate, PC- HOPE โ€” Tucson, Arizona
  • University of Arkansas for Medical Sciences โ€” Little Rock, Arkansas
  • City of Hope National Medical Center โ€” Duarte, California
  • UC San Diego Moores Cancer Center โ€” La Jolla, California
  • USC/Norris Comprehensive Cancer Center โ€” Los Angeles, California
  • Cedars Sinai Medical Center โ€” Los Angeles, California
  • Hoag Cancer Center โ€” Newport Beach, California
  • UC Irvine Health โ€” Orange, California
  • Stanford Cancer Center โ€” Palo Alto, California
  • University of California, Davis Comprehensive Cancer Center โ€” Sacramento, California
  • University of California Los Angeles (UCLA) โ€” Santa Monica, California
  • University of Colorado โ€” Aurora, Colorado
  • Yale Cancer Center โ€” New Haven, Connecticut
  • Florida Gynecologic Oncology/Regional Cancer Center โ€” Fort Myers, Florida
  • Mount Sinai Comprehensive Cancer Center โ€” Miami Beach, Florida
  • Emory University โ€” Atlanta, Georgia
  • Northeast Georgia Medical Center โ€” Gainesville, Georgia
  • Northwestern Medicine โ€” Chicago, Illinois
  • University of Illinois Cancer Center โ€” Chicago, Illinois
  • University of Chicago Medicine โ€” Chicago, Illinois
  • Carle Cancer Center โ€” Urbana, Illinois
  • Ascension St. Vicent Hospital, Inc. โ€” Indianapolis, Indiana

๐Ÿ“ž Contact the Study Coordinator

Phone: (617) 207-8976

Email: ACR-368-201ClinicalTrial@acrivon.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—