A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2) (NCT05552976)
A Phase 3, Two-stage, Randomized, Multicenter, Open-label Study Comparing Mezigdomide (CC-92480/BMS-986348), Carfilzomib, and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM): SUCCESSOR-2
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of the study is to compare Mezigdomide (CC-92480/BMS-986348) with carfilzomib and dexamethasone (MeziKD) against carfilzomib and dexamethasone (Kd) in the treatment of RRMM: SUCCESSOR-2.
Who can join: Review the eligibility criteria below.
Location: Local Institution - 0046 โ Mobile, Alabama
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (207 Sites)
Showing the first 25 of 207 sites.
- Local Institution - 0046 โ Mobile, Alabama
- Local Institution - 0005 โ Cerritos, California
- Local Institution - 0190 โ Irvine, California
- Local Institution - 0187 โ Los Angeles, California
- Local Institution - 0344 โ Santa Rosa, California
- Local Institution - 0339 โ Stockton, California
- Local Institution - 0279 โ Newark, Delaware
- Local Institution - 0341 โ Fort Myers, Florida
- Local Institution - 0342 โ St. Petersburg, Florida
- Local Institution - 0340 โ West Palm Beach, Florida
- Local Institution - 0348 โ Atlanta, Georgia
- Local Institution - 0291 โ Atlanta, Georgia
- Saint Alphonsus Regional Medical Center โ Boise, Idaho
- Local Institution - 0289 โ Annapolis, Maryland
- Local Institution - 0204 โ Boston, Massachusetts
- Local Institution - 0346 โ Minneapolis, Minnesota
- Local Institution - 0222 โ Little Silver, New Jersey
- Local Institution - 0199 โ The Bronx, New York
- Local Institution - 0322 โ Cleveland, Ohio
- Local Institution - 0172 โ Columbus, Ohio
- Local Institution - 0321 โ Providence, Rhode Island
- Local Institution - 0338 โ Greer, South Carolina
- Local Institution - 0349 โ Chattanooga, Tennessee
- Local Institution - 0323 โ Nashville, Tennessee
- Local Institution - 0337 โ Fort Worth, Texas
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Relapsed or Refractory Multiple Myeloma
- A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma โ Anchorage, Alaska
- A Study of JNJ-87562761 in Participants With Relapsed or Refractory Multiple Myeloma โ Toronto, Ontario
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma โ Tucson, Arizona
- A Modular, Phase I/II, Multicentre Study to Evaluate AZD4045, in Participants With Relapsed or Refractory Multiple Myeloma โ Duarte, California
- A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma โ Birmingham, Alabama
Explore by condition: All Relapsed or Refractory Multiple Myeloma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.