Combination Therapy to Improve SCI Recovery. (NCT05563103)
Breathing Low Oxygen to Enhance Spinal Stimulation Training and Functional Recovery in Persons With Chronic SCI: The BO2ST Trial
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to determine how combining bouts of low oxygen, transcutaneous spinal cord stimulation, and walking training may improve walking function for people with chronic spinal cord injury.
Who can join: Review the eligibility criteria below.
Location: Shirley Ryan AbilityLab — Chicago, Illinois
Age range: 18 Years to 70 Years
🧪 Interventions in This Study
- Daily acute intermittent hypoxia (OTHER)
- Room air (SHAM) (OTHER)
- Walking + tSTIM (OTHER)
- Walking + Sham transcutaneous spinal stimulation (tSHAM) (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- Shirley Ryan AbilityLab — Chicago, Illinois
- Spaulding Rehabilitation Hospital — Cambridge, Massachusetts
📞 Contact the Study Coordinator
Phone: (617) 952-6953
Email: npiazza2@mgb.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Spinal Cord Injuries
- Use of Point-of-care Neuro-sacral Electrophysiology Following Spinal Cord Injury — Montreal, Quebec
- Wearable Electrical Stimulation on the Back to Modulate Spinal Cord Activity — Philadelphia, Pennsylvania
- SCIVAX: Biomarkers of Immune Dysfunction and Vaccine Responsiveness in Chronic SCI — Manhasset, New York
- Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients — Rochester, Minnesota
- Standing, Stepping and Voluntary Movement Spinal Cord Epidural Stimulation — Louisville, Kentucky
- Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury — Cambridge, Massachusetts
Explore by condition: All Spinal Cord Injuries clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.