๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-11-27

A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC (NCT05611671)

A Phase 2b, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of 3 Active Dose Regimens of MORF-057 in Adults With Moderately to Severely Active Ulcerative Colitis (EMERALD-2)

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a Phase 2b randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of three active dose regimens of MORF-057 in adult patients with moderately to severely active Ulcerative Colitis (UC).

Who can join: Review the eligibility criteria below.

Location: Arizona Digestive Health - Sun City โ€” Sun City, Arizona

Age range: 18 Years to 85 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (102 Sites)

Showing the first 25 of 102 sites.

  • Arizona Digestive Health - Sun City โ€” Sun City, Arizona
  • Gastro Care Institute โ€” Lancaster, California
  • TLC Clinical Research Inc. โ€” Los Angeles, California
  • Innova Clinical Trials โ€” Coral Gables, Florida
  • Eminat, LLC - Miramar โ€” Miramar, Florida
  • Robert Wood Johnson University Medical School โ€” New Brunswick, New Jersey
  • Great Lakes Gastroenterology โ€” Mentor, Ohio
  • The University of Texas Health Science Center at Houston โ€” Houston, Texas
  • Blacktown Hospital โ€” Blacktown,
  • Concord Repatriation General Hospital โ€” Concord,
  • Royal Brisbane and Women's Hospital โ€” Herston,
  • Fiona Stanley Hospital โ€” Murdoch,
  • Mater Adult Hospital Brisbane โ€” South Brisbane,
  • Order Hospital Linz Ltd. - Hospital of Sisters of Mercy โ€” Linz,
  • Salzburg Regional Hospital โ€” Salzburg,
  • Medical University of Vienna โ€” Vienna,
  • Medical Center "Rusemed" EOOD โ€” Rousse,
  • University Multiprofile Hospital for Active Treatment "ACIBADEM City Clinic" โ€” Sofia,
  • Acibadem City Clinic Multiprofile Hospital for Active Treatment Tokuda โ€” Sofia,
  • Second Multiprofile Hospital for Active Treatment - Sofia โ€” Sofia,
  • PreventaMed, s.r.o. โ€” Olomouc,
  • Clinoxus s.r.o., Outpatient Clinic Budejovicka โ€” Prague,
  • LV Venter OU โ€” Pรคrnu,
  • OU Innomedica โ€” Tallinn,
  • East Tallinn Central Hospital โ€” Tallinn,

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—