High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans (NCT05625204)
🩺 Plain-English Summary (8th-Grade Level)
Frailty is defined as a greater susceptibility to stressors resulting from age-related impairments in adaptive biological systems. Frailty leads to poorer physical performance and functional capacity and higher risk of adverse outcomes including falls, hospitalization, and mortality. Resilience, defined as the capacity to recover from disruptions to homeostasis, is critical to successful aging because it precedes frailty and enhances adults' ability to maintain optimal health and function well into older age. Evidence- based therapies to help older adults enhance resilience are limited and the biological underpinnings contributing to improved resilience have not yet been fully characterized. To address this important need, the investigators will conduct a clinical trial to examine the benefits of center- and home-based high intensity interval training (HIIT) on functional capacity, frailty, and resilience, and also to identify novel biomarkers of resilience in older Veterans.
Who can join: Review the eligibility criteria below.
Location: Kansas City VA Medical Center, Kansas City, MO — Kansas City, Missouri
Age range: 65 Years
🧪 Interventions in This Study
- Center based attention (stretching only) control (BEHAVIORAL)
- Center based HIIT (BEHAVIORAL)
- Home based HIIT (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- Kansas City VA Medical Center, Kansas City, MO — Kansas City, Missouri
- Kansas City VA Medical Center, Kansas City, MO — Kansas City, Missouri
📞 Contact the Study Coordinator
Phone: (716) 888-4869
Email: Kenneth.Seldeen@va.gov
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Frailty
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- The PREPARE Trial: Exercise Before Surgery to Improve Recovery in Older People With Frailty — Ottawa, Ontario
- Voice-Activated Technology to Improve Mobility in Multimorbid, Frail, Homebound Older Adults (EngAGE) — Chicago, Illinois
- The Effect of the COVID-19 Pandemic on Frailty in Liver Transplant Candidates — Dallas, Texas
- An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer — Memphis, Tennessee
Explore by condition: All Frailty clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.