Trauma Resuscitation With Low-Titer Group O Whole Blood or Products (NCT05638581)
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to compare the effectiveness of unseparated whole blood (referred to as Low-Titer Group O Whole Blood) and the separate components of whole blood (including red cells, plasma, platelets, and cryoprecipitate) in critically injured patients who require large-volume blood transfusions.
Who can join: Review the eligibility criteria below.
Location: University of Alabama at Birmingham, UAB Hospital — Birmingham, Alabama
Age range: 15 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (13 Sites)
- University of Alabama at Birmingham, UAB Hospital — Birmingham, Alabama
- Los Angeles County + University of Southern California (LAC + USC) Medical Center — Los Angeles, California
- University Medical Center New Orleans LCMC Health — New Orleans, Louisiana
- University of Maryland Medical Center — Baltimore, Maryland
- Washington University School of Medicine — St Louis, Missouri
- Atrium Health Wake Forest Baptist — Winston-Salem, North Carolina
- University of Cincinnati Medical Center — Cincinnati, Ohio
- Oregon Health and Sciences University Hospital — Portland, Oregon
- Penn Presbyterian Medical Center — Philadelphia, Pennsylvania
- University of Texas Health Science Center Houston — Houston, Texas
- University of Texas Health San Antonio and University Health System — San Antonio, Texas
- Harborview Medical Center — Seattle, Washington
- Froedtert Hospital — Milwaukee, Wisconsin
📞 Contact the Study Coordinator
Phone: (205) 934-5890
Email: swstephens@uabmc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.