🏛️ Verified NIH Record • Updated 2025-10-09

SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors (NCT05642780)

A Multicenter, Open-label, Phase 2, Basket Study to Evaluate the Efficacy and Safety of SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors

🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Klus Pharma Inc.

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the efficacy and safety of combination of SKB264 and Pembrolizumab in patients with selected solid tumors including cervical cancer, urothelial cancer, ovarian cancer, prostate cancer,advanced endometrial cancer.

Who can join: Review the eligibility criteria below.

Location: Community Clinical Research Center — Anderson, Indiana

Age range: 18 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (48 Sites)

Showing the first 25 of 48 sites.

  • Community Clinical Research Center — Anderson, Indiana
  • Norton Cancer Institute — Louisville, Kentucky
  • Anne Arundel Medical Center (AAMC) — Annapolis, Maryland
  • UT Health East Texas - Hope Cancer Center Tyler — Tyler, Minnesota
  • Westchester Medical Center — Hawthorne, New York
  • Texas Oncology, P.A. Amarillo, TX — Amarillo, Texas
  • Texas Oncology, P.A. Austin, TX — Austin, Texas
  • Oncology & Hematology Associates of Southwest Virginia, Inc. Roanoke, VA — Roanoke, Virginia
  • Icon Cancer Centre Wesley — Auchenflower, Queensland
  • Flinders Medical Centre — Bedford Park,
  • Wollongong Hospital — Kogarah,
  • Algemeen Ziekenhuis Klina — Brasschaat,
  • Grand Hôpital de Charleroi - Site Notre-Dame — Charleroi,
  • Cliniques Universitaires Saint-Luc — Woluwe-Saint-Lambert,
  • BC Cancer - Kelowna — Kelowna, British Columbia
  • Centre Hospitalier de l'Université de Montréal (CHUM) — Montreal,
  • Sun Yat-Sen University Cancer Center — Guangzhou, Guangdong
  • Affiliated Cancer Hospital of Guangxi Medical University — Nanning, Guangxi
  • Hubei Cancer Hospital — Wuhan, Hubei
  • Hunan Cancer Hospital — Changsha, Hunan
  • Jilin Cancer Hospital — Changchun, Jinlin
  • The Second Hospital of Dalian — Dalian, Liaoning
  • Weifang People's Hospital — Weifang, Shandong
  • The First Affiliated Hospital of Xi'an Jiaotong University — Xi’an, Shanxi
  • Beijing Obstetrics and Gynecology Hospital, Capital Medical University — Beijing,

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Solid Tumor clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗