A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus (NCT05672576)
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Safety, and Tolerability of Cenerimod in Adult Subjects With Moderate-to-severe Systemic Lupus Erythematosus (SLE) on Top of Background Therapy
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to see how well cenerimod reduces symptoms of Systemic Lupus Erythematous in adult patients with moderate to severe symptoms. The main questions it aims to answer are: * How well cenerimod works on top of the treatment already being administered. * How safe cenerimod is for adult patients with Systemic Lupus Erythematosus. Researchers will compare one dose of cenerimod and a placebo to see how well cenerimod works when it is added to the treatment already being administered. In this research study approximately 210 participants will receive cenerimod and approximately 210 participants will receive placebo for 12 months.
Who can join: Review the eligibility criteria below.
Location: Tucson Clinical Research Institute, LLC — Tucson, Arizona
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (147 Sites)
Showing the first 25 of 147 sites.
- Tucson Clinical Research Institute, LLC — Tucson, Arizona
- UCSD Perlman Medical Offices — La Jolla, California
- Amicis Research Center — Northridge, California
- Hope Clinical Trials, Inc. — Coral Gables, Florida
- Vital Pharma Research — Hialeah, Florida
- Tectum Medical Research — Hollywood, Florida
- Alloy Clinical Research, LLC — Kissimmee, Florida
- Allied Biomedical Research Institute — Miami, Florida
- D&H National Research Centers INC — Miami, Florida
- Professional research Center INC — Miami, Florida
- San Marcus Research Clinic, Inc. — Miami Lakes, Florida
- Tandem Clinical Research — Marrero, Louisiana
- RB Wellness Clinic — Las Vegas, Nevada
- Columbia University Medical Center — New York, New York
- Precision Comprehensive Clinical Research Solutions — Colleyville, Texas
- Texas Arthritis Center — El Paso, Texas
- Northwest Houston Arthritis Center — Houston, Texas
- Biomedica Research Group — Providencia,
- Sociedad Médica del Aparato Locomotor S. A. — Providencia,
- Estudios G y C Ltda — Santiago,
- Enroll SpA — Santiago,
- Centro de Especialidades Medicas Vanguardia — Temuco,
- Clinical Research Chile SpA — Valdivia,
- Hospital San José de Victoria — Victoria,
- iMedica s.r.o. — Brno,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Lupus Erythematosus, Systemic
- A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE) — Phoenix, Arizona
- Interactive Digital Technology to Assess and Improve Cognitive Dysfunction in Patients With Systemic Lupus Erythematosus — Denver, Colorado
- A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus — Homewood, Alabama
- Engagement in CHildhood-Onset Systemic Lupus — The Bronx, New York
- A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus — Huntington Park, California
Explore by condition: All Lupus Erythematosus, Systemic clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.