Metabolic and Inflammatory Outcomes of the Ketogenic Diet Comparing Saturated and Unsaturated Fat Sources (NCT05681468)
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to compare a healthy KETO diet supplemented with canola oil (KETO-Can) compared to a traditional KETO diet high in saturated fat (KETO-Sat) and low-fat diet (LFD) in adults at high risk of or diagnosed with type 2 diabetes. The main question\[s\] it aims to answer are: * Effects on CVD risk factors (plasma cholesterol, TG, ApoB100, glucose, insulin and HbA1C). * Effects on systemic inflammation and immune function. * Adherence to interventions. Participants will be randomized into 1 of the dietary treatments during which they will follow a Keto or a low-fat diet. Comparisons among groups at 3 and 6 months of intervention will be conducted.
Who can join: Review the eligibility criteria below.
Location: University of Alberta — Edmonton, Alberta
Age range: 18 Years to 70 Years
🧪 Interventions in This Study
- Keto-SAT (OTHER)
- Keto-CAN (OTHER)
- LFD (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Alberta — Edmonton, Alberta
📞 Contact the Study Coordinator
Phone: (780) 492-9506
Email: blancoce@ualberta.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in PreDiabetes
- Randomized Trial of Exercise Promotion in Primary Care — Pasadena, California
- Monounsaturated Fatty Acid Supplementation for Overweight and Obese Individuals With Prediabetes — Boston, Massachusetts
- Pharmacists' Delivery of Education to Prevent Diabetes in the New Orleans Hospitality Industry — New Orleans, Louisiana
- Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components — Columbus, Ohio
- Behavioral Nudges for Diabetes Prevention (BEGIN) Trial in Primary Care — Chicago, Illinois
- The YMCA Healthy Lifestyle Program for Prediabetes — Port Huron, Michigan
Explore by condition: All PreDiabetes clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.