๐๏ธ Verified NIH Record โข Updated 2026-06-11
Water Vapor Ablation for Localized Intermediate Risk Prostate Cancer (NCT05683691)
Prospective, Multicenter, Single-Arm Study of VanquishTM Water Vapor Ablation for PrOstate CanceR
๐ต Active, Not Recruiting Observational / Diagnostic โ๏ธ Medical Device Protocol Sponsor: Francis Medical Inc.
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the safety and efficacy of the Vanquish Water Vapor Ablation Device ("Vanquish") in treating subjects with Gleason Grade Group 2 (GGG2) localized intermediate-risk prostate cancer.
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic- Phoenix โ Phoenix, Arizona
Age range: 50 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (25 Sites)
- Mayo Clinic- Phoenix โ Phoenix, Arizona
- Memorial Care โ Laguna Hills, California
- University of Southern California โ Los Angeles, California
- Kasraeian Urology โ Jacksonville, Florida
- University of Chicago โ Chicago, Illinois
- Wichita Urology โ Wichita, Kansas
- Chesapeake Urology โ Baltimore, Maryland
- Johns Hopkins โ Baltimore, Maryland
- Corewell Health / William Beaumont University Hospital โ Royal Oak, Michigan
- Michigan Institute of Urology โ Troy, Michigan
- University of Minnesota โ Minneapolis, Minnesota
- Mayo Clinic- Rochester โ Rochester, Minnesota
- Minnesota Urology โ Woodbury, Minnesota
- NYU Langone Health โ New York, New York
- Northwell Health- Lenox Hill Hospital โ New York, New York
- University of Rochester โ Rochester, New York
- Duke Cancer Institute โ Durham, North Carolina
- The Urology Group โ Cincinnati, Ohio
- MidLantic Urology โ Bala-Cynwyd, Pennsylvania
- Carolina Urologic Research Center โ Myrtle Beach, South Carolina
- Urology Austin โ Austin, Texas
- Houston Methodist Hospital and Research Institute โ Houston, Texas
- The Urology Place โ San Antonio, Texas
- Urology of Virginia, PLLC โ Virginia Beach, Virginia
- Medical College of Wisconsin โ Milwaukee, Wisconsin
๐ Contact the Study Coordinator
Phone: (800) 664-4580
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- A Study in Which Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) Patients for Whom a Decision to Treat With Darolutamide Has Been Made Before Enrollment Are Observed and Certain Outcomes Are Described โ Homewood, Alabama
- Stereotactic Ablative Radiation Therapy for Prostate Cancer โ Charleston, South Carolina
- A Study of Stereotactic Body Radiation Therapy (SBRT) Without Androgen Deprivation Therapy (ADT) in People With Unfavorable Intermediate-Risk Prostate Cancer โ Basking Ridge, New Jersey
- A Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib (LY2835219) in Participants With Prostate Cancer โ Phoenix, Arizona
- Neoadjuvant Enoblituzumab (MGA271) in Men With Localized Intermediate and High-Risk Prostate Cancer โ Baltimore, Maryland
Explore by condition: All Prostate Cancer clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.