๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-11

Water Vapor Ablation for Localized Intermediate Risk Prostate Cancer (NCT05683691)

Prospective, Multicenter, Single-Arm Study of VanquishTM Water Vapor Ablation for PrOstate CanceR

๐Ÿ”ต Active, Not Recruiting Observational / Diagnostic โš™๏ธ Medical Device Protocol Sponsor: Francis Medical Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the safety and efficacy of the Vanquish Water Vapor Ablation Device ("Vanquish") in treating subjects with Gleason Grade Group 2 (GGG2) localized intermediate-risk prostate cancer.

Who can join: Review the eligibility criteria below.

Location: Mayo Clinic- Phoenix โ€” Phoenix, Arizona

Age range: 50 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (25 Sites)

  • Mayo Clinic- Phoenix โ€” Phoenix, Arizona
  • Memorial Care โ€” Laguna Hills, California
  • University of Southern California โ€” Los Angeles, California
  • Kasraeian Urology โ€” Jacksonville, Florida
  • University of Chicago โ€” Chicago, Illinois
  • Wichita Urology โ€” Wichita, Kansas
  • Chesapeake Urology โ€” Baltimore, Maryland
  • Johns Hopkins โ€” Baltimore, Maryland
  • Corewell Health / William Beaumont University Hospital โ€” Royal Oak, Michigan
  • Michigan Institute of Urology โ€” Troy, Michigan
  • University of Minnesota โ€” Minneapolis, Minnesota
  • Mayo Clinic- Rochester โ€” Rochester, Minnesota
  • Minnesota Urology โ€” Woodbury, Minnesota
  • NYU Langone Health โ€” New York, New York
  • Northwell Health- Lenox Hill Hospital โ€” New York, New York
  • University of Rochester โ€” Rochester, New York
  • Duke Cancer Institute โ€” Durham, North Carolina
  • The Urology Group โ€” Cincinnati, Ohio
  • MidLantic Urology โ€” Bala-Cynwyd, Pennsylvania
  • Carolina Urologic Research Center โ€” Myrtle Beach, South Carolina
  • Urology Austin โ€” Austin, Texas
  • Houston Methodist Hospital and Research Institute โ€” Houston, Texas
  • The Urology Place โ€” San Antonio, Texas
  • Urology of Virginia, PLLC โ€” Virginia Beach, Virginia
  • Medical College of Wisconsin โ€” Milwaukee, Wisconsin

๐Ÿ“ž Contact the Study Coordinator

Phone: (800) 664-4580

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Prostate Cancer clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—