Mechanisms Preventing Pharyngeal Reflux (NCT05696184)
Pathophysiology of Pharyngo-esophageal Junction and Esophageal Mechanisms Preventing Pharyngeal Reflux of Gastric Content
🩺 Plain-English Summary (8th-Grade Level)
The overall goal is to define and characterize the manometric characteristics of UES incompetence associated with objectively documented pharyngeal reflux. The investigators will use endoscopic reflux detection as gold standard.
Who can join: Review the eligibility criteria below.
Location: Medical College of Wisconsin — Milwaukee, Wisconsin
Age range: 18 Years to 85 Years
🧪 Interventions in This Study
- Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy (DIAGNOSTIC_TEST)
- Slow and rapid intra-esophageal infusion (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Medical College of Wisconsin — Milwaukee, Wisconsin
📞 Contact the Study Coordinator
Phone: (414) 955-6840
Email: rshaker@mcw.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in GERD
- Multicenter Single-Blind RCT of CTIF Versus LNF For Treatment of GERD in Patients Requiring Hiatal Hernia Repair — Irvine, California
- Long Term Outcomes of Bariatric Patients Treated With Surgery or Endoscopy — Baltimore, Maryland
- PROPER-GERD: A Prospective Crossover Study to Evaluate Probe Placement Optimization for Reflux Testing in Women and Lower-BMI Patients — Chicago, Illinois
- Antireflux Surgery Without Preoperative Esophageal Manometry — Cleveland, Ohio
- Compassionate Use of Domperidone for Refractory Gastroparesis — Kansas City, Missouri
Explore by condition: All GERD clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.