๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-05-31

Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients (NCT05703971)

A Phase 1/2 Clinical Trial of Quaratusugene Ozeplasmid and Atezolizumab Maintenance Therapy in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC)

๐ŸŸข Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Genprex, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This clinical trial will evaluate the combination of quaratusugene ozeplasmid with atezolizumab as maintenance therapy for patients with Extensive Stage Small Cell Lung Cancer (ES-SCLC). The study is comprised of 2 phases, a dose selection phase (Phase 1) and a safety and efficacy evaluation phase (Phase 2).

Who can join: Review the eligibility criteria below.

Location: Rocky Mountain Cancer Centers, LLP โ€” Lone Tree, Colorado

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (17 Sites)

  • Rocky Mountain Cancer Centers, LLP โ€” Lone Tree, Colorado
  • Washington University School of Medicine - Siteman Cancer Center โ€” St Louis, Missouri
  • Gabrail Cancer Center Research โ€” Canton, Ohio
  • Oncology_Hematology Care Clinical Trials, LLC โ€” Cincinnati, Ohio
  • Oncology_Hematology Care Clinical Trials, LLC โ€” Cincinnati, Ohio
  • Oncology_Hematology Care Clinical Trials, LLC โ€” Cincinnati, Ohio
  • Oncology_Hematology Care Clinical Trials, LLC โ€” Cincinnati, Ohio
  • Oncology_Hematology Care Clinical Trials, LLC โ€” Fairfield, Ohio
  • Willamette Valley Cancer Institute (Oregon) โ€” Eugene, Oregon
  • Northwest Cancer Specialists, P.C. โ€” Portland, Oregon
  • Providence Cancer Institute โ€” Portland, Oregon
  • Northwest Cancer Specialists, P.C. โ€” Portland, Oregon
  • Northwest Cancer Specialists, P.C. โ€” Tigard, Oregon
  • Texas Oncology - DFW โ€” Dallas, Texas
  • Texas Oncology - Northeast Texas โ€” Tyler, Texas
  • Virginia Cancer Specialists, PC โ€” Fairfax, Virginia
  • Northwest Cancer Specialists, P.C. โ€” Vancouver, Washington

๐Ÿ“ž Contact the Study Coordinator

Phone: 1-877-774-GNPX

Email: kcombs@genprex.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—