๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-11-17

A Study of Ruxolitinib in Combination With Abemaciclib for the Treatment of Myelofibrosis (NCT05714072)

A Phase I Study of Ruxolitinib Plus Abemaciclib for Patients With Primary or Post-polycythemia Vera/Essential Thrombocythemia Myelofibrosis

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Memorial Sloan Kettering Cancer Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The study is being done to see if the combination of ruxolitinib and abemaciclib is a safe and effective treatment for people with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis.

Who can join: Review the eligibility criteria below.

Location: Memorial Sloan Kettering Basking Ridge โ€” Basking Ridge, New Jersey

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (7 Sites)

  • Memorial Sloan Kettering Basking Ridge โ€” Basking Ridge, New Jersey
  • Memorial Sloan Kettering Monmouth โ€” Middletown, New Jersey
  • Memorial Sloan Kettering Bergen โ€” Montvale, New Jersey
  • Memorial Sloan Kettering Suffolk - Commack โ€” Commack, New York
  • Memorial Sloan Kettering Westchester โ€” Harrison, New York
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • Memorial Sloan Kettering Nassau (Limited Protocol Activities) โ€” Uniondale, New York

๐Ÿ“ž Contact the Study Coordinator

Phone: (646) 608-3746

Email: rampalr@mskcc.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—