๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-04-29

Shortened Course Adjuvant Radiotherapy Following TORS (NCT05714657)

A Phase II Study of Shortened Course, Dose De-Intensified Adjuvant Radiotherapy Following Transoral Robotic Surgery (TORS) and Neck Dissection for HPV-Associated Oropharyngeal Squamous Cell Carcinoma

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ“‹ Clinical Research Protocol Sponsor: Abramson Cancer Center at Penn Medicine

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a single-arm, phase II study to establish the safety of reducing radiation dose in selected HPV-Associated OPSCC patients receiving adjuvant radiation after TORS and neck dissection. This protocol also allows for sparing of the primary resection bed, in appropriate patients, as previously published by our group and found to be safe and effective.

Who can join: Review the eligibility criteria below.

Location: Lancaster General Hospital โ€” Lancaster, Pennsylvania

Age range: 18 Years

๐Ÿงช Interventions in This Study

  • Shortened Course Adjuvant Radiotherapy Following TORS (RADIATION)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (3 Sites)

  • Lancaster General Hospital โ€” Lancaster, Pennsylvania
  • University of Pennsylvania โ€” Philadelphia, Pennsylvania
  • Pennsylvania Hospital โ€” Philadelphia, Pennsylvania

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—