Blinded Efficacy and Safety Study of CAL02 IV Plus SOC in Subjects With Severe Community-Acquired Bacterial Pneumonia (NCT05776004)
A Randomized, Double-Blind, Placebo-Controlled Multicenter Study to Evaluate the Efficacy and Safety of CAL02 Administered Intravenously in Addition to Standard of Care in Subjects With Severe Community-Acquired Bacterial Pneumonia (SCABP)
🩺 Plain-English Summary (8th-Grade Level)
This is a placebo-controlled study to evaluate the addition of CAL02 to standard of care in treating hospitalized subjects diagnosed with severe community acquired bacterial pneumonia (SCABP) requiring critical care measures
Who can join: Review the eligibility criteria below.
Location: UCSF Hospital — Fresno, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (90 Sites)
Showing the first 25 of 90 sites.
- UCSF Hospital — Fresno, California
- UF Health Shands Hospital — Gainesville, Florida
- Northwestern Memorial Hospital — Chicago, Illinois
- University of Nebraska Medical Center — Omaha, Nebraska
- Wake Forest Baptist Health Hospital — Winston-Salem, North Carolina
- Cleveland Clinic Fairview Hospital — Cleveland, Ohio
- University of Texas Medical Branch — Galveston, Texas
- Hospital Interzonal General de Agudo Dr Jose Pena — Bahía Blanca, Buenos Aires
- Hospital Italiano de Buenos Aires — Ciudad Autonoma de Buenos Aires, Buenos Aires
- Hospital Misericordia Nuevo Siglo — Córdoba,
- Hospital Central — Mendoza,
- Clinique Universitaire Saint Luc — Brussels,
- Clinique Saint Pierre — Ottignies,
- Chu-Ucl-Namur — Yvoir,
- Hospital Mae de Deus — Porto Alegre, Rio Grande do Sul
- Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto — São José do Rio Preto, São Paulo
- Unidade de Pesquisa Clinica da Faculdade de Medicina de Botucatu — Botucatu,
- Hospital do Servidor Publico Estadual — São Paulo,
- Foothills Hospital Medical Centre — Calgary, Alberta
- Peter Lougheed Centre — Calgary, Alberta
- Rockyview General Hospital — Calgary, Alberta
- South Health Campus Hospital — Calgary, Alberta
- Saint Paul's Hospital — Vancouver,
- Pontificia Universidad Catolica de Chile — Santiago,
- Centro de Investigacion Clinica de la Costa SAS — Barranquilla,
📞 Contact the Study Coordinator
Phone: (877) 827-3222
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Pneumonia, Bacterial
- Discharge Stewardship in Children's Hospitals — St Louis, Missouri
Explore by condition: All Pneumonia, Bacterial clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.